Inisalini insulin

Taʻu fefaʻatauaʻiga o sauniuniga: Inisinia o inisalini-isophan (Insulin-isophan biosynthetic human)

Talosaga Faavaomalo Faavaomalo: Inisalini + Isofan

Faiga o foliga: faʻamalologa mo pulega faʻapitoa

Mea aoga: insulin + isophane

Pharmacotherapeutic group: galue malosi-inisalini

Gaioiga faʻamaloilo:

Inisalini le tumau. Faʻaititia le maualuga o le kulukose i totonu o le toto, faʻateleina lona faʻaaogāina e masini, faʻaleleia le lipogenesis ma le glycogenogenesis, faʻasologa o le protein, e faʻaitiitia ai le fua o le kulukose i le ate.

E fesoʻotaʻi ma se faʻamaumauga faapitoa i luga o le pito i fafo o sela ma fai ai se faʻalavelave faʻapipiʻi insulin. E ala i le faʻagaoioia o le faʻapipiʻi o le CAMP (i totonu o suauʻu gaʻo ma lela o le ate) poʻo le tuusao saʻo i totonu o le masini (maso), o le inisalini receptor complex stimulates processes intracellular, e aʻafia ai sifi o se numera o enzymes autu (hexokinase, pyruvate kinase, glycogen synthetase, ma isi). O le faʻaitiitia o le kulukose o le toto ona o le faateleina o lana avega o le intracellular, faʻalauteleina le faʻafefe ma le faʻasiliina o masini, faʻamalosi o le lipogenesis, glycogenogenesis, synthesis synthesis, o le faʻaitiitia o le fua o le kulukose (gase i le glycogen), ma isi.

A maeʻa le tui, o le aafiaga e tupu i le 1-1.5 itula O le maualuga o le aafiaga i le va o le 4-12 itula, o le umi o le gaoioiga e 11-24 itula, e fuafua i le tuufaatasiga o le inisalini ma le fualaau, e atagia ai le vavalalata ma le vavalalata.

Faailoga mo le faʻaaogaina:

Ituaiga 1 maʻisuka.

O le maʻisuka ituaiga 2, tulaga o le tetee atu i vailaau oona, o le tetee atu i vailaʻau oona (hypoglycemic drugs), faʻamaʻi pipisi, togafitiga faʻapipiʻi (faʻasolosolo faʻatasi), maʻi o le maʻisuka i le taimi o maitaga (e leai se aoga o togafitiga).

Contraindications:

Hypersensitivity, hypoglycemia, insulinoma.

Faʻamatalaga ma pulega:

P / C, 1-2 taimi i le aso, 30-45 minute aʻo leʻi faia le taeao (sui le tui tui i taimi uma). I tulaga faapitoa, e mafai e le fomaʻi ona fautuaina se / m tui o le fualaau faasaina. I / i le faʻaofiina o le inisalini o le umi ole taimi e faʻasaina! O meaola e filifilia taitoatasi ma faalagolago i le kulūkose i totonu o le toto ma le urine, o uiga o le kosi o le maʻi. E masani lava, o laasaga e 8-24 IU 1 le taimi i le aso. I tagata matutua ma tamaiti e maualuga lo latou malamalama ile inisalini, o se fua ole laʻititi ole 8 IU / aso e mafai ona lava, i tagata gasegase e faʻaitiitia le lagona lelei - e silia ma le 24 IU / aso. I fualaau o aso taʻitasi e sili atu i le 0.6 IU / kg, - i le ituaiga 2 injections i nofoaga eseese. Tagata mamaʻi e maua le 100 IU pe sili atu i le aso, pe a sui le inisalini, e fautuaina le falemai. Faʻafeiloaʻi mai le tasi vailaʻau i le isi e tatau ona faia i lalo o le puleaina o le kulukose toto.

Itū taua:

I le tulaga o le solia o tulafono faatonutonu, meaʻai, faʻamalositino malosi, faʻamaʻi faʻamaʻi, o le atinaʻeina o le hypoglycemia e ono mafai, i mataupu sili ona ogaoga - faʻamuamua ma au.

Masalo: gasegase o le tino, lanu - mumu ma le vevela, lautele - anaphylactoid reactions.

Fesootaiga ma isi fualaau faasaina:

Faʻataʻitaʻiga e feteʻenaʻi ma vailaʻau o isi fualaau. O le aafiaga o le hypoglycemone e faʻaleleia e sulfonamides (e aofia ai vailaau oona, o le sulponeamides), o le MAO (e aofia ai furazolidone, procarbazin, selegiline), carbonic anhydrase inhibitors, inhibitors ACE, NSAID (including salicylates), anabolic (e aofia ai stanozolol, oxandrolone, methandrostenolone), androgens, bromocriptine, tetracyclines, clofibrate, ketoconazole, mebendazole, theophylline, cyclophosphamide, phenfluramine, Li + preparations, pyridoxine, quinidine, quinine, chloroquinine, et. aafiaga Hypoglycemic o glucagon faaletonu, hormone tuputupu ae, corticosteroids, contraceptives tuufofoga, estrogens, thiazide ma diuretics matasele, BCCI, homone thyroid, heparin, sulfinpyrazone, sympathomimetics, danazol, tricyclics, clonidine, tagata tetee kalisiu, diazoxide, morphine, mariuana, nicotine, phenytoin, epinephrine, H1-histamine receptor blockers.

Beta-blockers, reserpine, octootide, pentamidine e mafai ona faʻaleleia ma faavaivaia le aafiaga o le hypoglycemic insulin.

Tulaga o le teuina mo le fualaau faasaina:

I totonu o le pusaaisa, i le vevela o le 2-8 ° C (aua nei togi). Taofi ese mai le aapa atu o tamaiti.

Aso faʻauma: 2 tausaga

Aua le faʻaaoga pe a maeʻa le aso na faʻauʻuina i luga o le afifi.

Tuutuʻuga o faʻatagaga mai falemaʻi: Faʻamatalaga

Foafoa: ICN Jugoslavija, Yugoslavia